What to prescribe for itching due to jaundice??

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Calamine lotion for local application Levocet sos

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Itching or pruritus is common in obstructive jaundice It is presumed to be because of accumulation of bile salt in Dermis, other mechanism proposed are through stimulation of serotonergic pathway, Treatment of obstruction of obstructive jaundice is most important way of treating itching Other molecules used are 1) Cholestyramine - bind to bile salt and reduce absorption 2) Antihistaminic 3) SSRI - Selective serotonin reuptake inhibitor 4) Gabapentin

Sir the patient has undergone cholecystectomy about 2yrs back and the usg report is also clean ruling out obstruction
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Current guidelines for the treatment of itching in jaundice recommend initial management with biliary drainage where possible and medical management with ursodeoxycholic acid, followed by cholestyramine, rifampicin, naltrexone and sertraline.

Symptomatic treatment, locally calamine Powder may be safe

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AQUASOFT CV LOTION APPLY LOCALLY TWICE TAB Levocet 5mg bd

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Calapure lotion / urtiplex lotion antihistamine drug

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Tab Hepasulfol AA 1bd Calamine lotiom Cetrizine,1bd

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Simple Calamine lotion &/Fexafedine 180.mg.OD.

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Anti allergic ursodeoxycholic acid Calamine

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Calapure A lotion Levocetrizine 10mg od

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