Why platelet comedown due to any infection?
Viruses can trigger a decrease in platelet production by (I) infection of megakaryocytes, which can lead to (A) apoptosis of megakaryocytes, (B) decreased maturation and ploidy of megakaryocytes, or (C) decreased expression of thrombopoietin receptor c-Mpl..
SPLEEN IS A ORGAN OF IMMUNITY.. IN INFECTION..BLOOD FILTERED IN SPLEEN.. THIS ENLARGED SPLEEN..CAN.. HARBOR ..TOO MUCH PLATELETS..
Not necessarily. Infections often cause reactive thrombocytosis
Apparently not necessary, differs with different infections
NO... PLATELETS. COUNT DIFFER. WITH TYPES. OF. INFECTIONS AND ANTIBIOTICS. ALSO... ANTIPLATELETS. MEDICATIONS
Yes, infection, spleen disorder,use of antiplatelets drugs.
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