46 xx testicular disorders of sex development
Presence of testes in an individual with a 46,XX karyotype, typically associated with translocation of the SRY gene, encoding the transcription factor sex-determining region Y protein, from the paternal Y chromosome to the paternal X chromosome during gametogenesis (SRY-positive). Approximately 15-20% of individuals with 46,XX testicular DSD are SRY-negative. These individuals may have other genetic variations affecting testis determination, such as duplication of the SOX9 gene, which encodes the transcription factor SOX-9.
Disease Alternative Name
Trending Diseases
Trending Cases
- Login to View the image
Epididymal cysts are fluid filled sacs that develop in the Epididymis. They occur for a number of reasons but are always benign and generally cause mild discomfort only. Dr. Vivek Jha is sharing a clinical case of "Epididymal cyst" managed with surgical expertise by him. Share your views on the case & learn new things.
Expert Insights8 Likes14 Answers - Login to View the image
F.60yrs. LBA with swelling of legs. 3months.
Dr. Syam Sundar Patro1 Like5 Answers - Login to View the image
X-rays are commonly used in clinical practice to diagnose fractures. Characteristics of the fracture such as the type, deformity & soft tissue / joint involvement are used to guide management. Learn & update your basic radiological approach for “Bone Fractures” & interpretation knowledge & patient care approach with this post.
Radiology Essential3 Likes2 Answers - Login to View the image
Check how quickly can you solve these questions using your clinical knowledge. Solve & get a chance to be the top performer. We are Live Now.
Curofy Quiz0 Like0 Answer - Login to View the image
Check out the answer for Quick Brains quiz.
Curofy Quiz0 Like0 Answer