5-aminolevulinic acid dehydratase deficiency porphyria

A topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. (NCI04)

Disease Alternative Name

aminolevulinic acid
5-ala
5-amino-4-oxopentanoic acid
5-aminolevulinic acid
delta aminolevulinic acid
delta-aminolevulinic acid
d-amino-levulinic acid
5-aminolaevulinic acid
amino-levulinic acid
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