Acrokeratoderma hereditary papulotranslucent

A melanoma defined by the presence of multiple cases of cutaneous melanoma among blood-relatives on the same side of the family. It is caused by germline mutations in the CDKN2A or CDK4 genes. It is associated with an increased risk of pancreatic cancer in a subset of CDKN2A families (WHO, 2006).

Disease Alternative Name

familial cutaneous melanoma
hereditary melanoma
hereditary cutaneous melanoma
familial melanoma
hereditary cutaneous (skin) melanoma

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