Aicar transformylase inosine monophosphate cyclohydrolase deficiency

A family of enzymes that converts inosine monophosphate to xanthosine monophosphate. This reaction is the rate limiting step in de novo guanosine triphosphate (GTP) synthesis.

Disease Alternative Name

imp oxidoreductase
inosine monophosphate oxidoreductase
imp dehydrogenase
inosine monophosphate dehydrogenase
impdh
ec 1.1.1.205
inosinate dehydrogenase
imp:nad+ oxidoreductase
inosinic acid dehydrogenase
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