Glioblastoma

The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma, IDH-mutant), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma, IDH- wildtype). (Adapted from WHO)

Disease Alternative Name

spongioblastoma multiforme
gbm (glioblastoma)
cns
glioblastoma (gbm)
who grade iv glioma
grade iv astrocytic tumor
grade iv astrocytoma
grade iv astrocytic neoplasm
gbm
MainRecentTopDoctors
Concluded Case

23 yrs female,with rt fronto parietal Glioblastoma multiformes.MRI suggestive of rt PCA infarct,what could be the cause ...See More

144 Views

, 1 Like

, 7 Answers

Concluded answer

Brain edema raised ICP and 2ndary vascular compromise and PCA infarction. Kernohan notch - a radiological findings due to midline shift due to mass effect resulting in compression of contralateral cerebral crust by tentorium cerebelli resu...


Concluded Case

NEw case ,Last case seen on 19th Nov, OPD at 3.30 pm. 24 yr old ,Doctor ,preparing for PG exam , came back today ( ...See More

97 Views

, 5 Answers

Concluded answer

Thanks for the answers. Admitted and received 2doses of metyl pred, Iv 1gr each. Father of pt is also a doctor. Discussed with others . Majority suggested Stereotactic biopsy which is not available here and hence transferred to near b...


Recent Cases of Glioblastoma

Browse recently discussed Glioblastoma cases by specialists

Top Cases of Glioblastoma

Selected by editors, top cases are known for unique problem or best solution

Top Glioblastoma Doctors on Curofy

Top doctors who continously share their opinions on Glioblastoma
Trivandrum
1313 followers

Kerala Institute of Medical Sciences

Professor and Senior Consultant Neurology

Medical College Thiruvananthapuram

MBBS,MD (Med) ,DM(Neurology),DNB(Neurology), FAAN(Fellow of American Academy of Neurology)

User Languages
Speaks English, Hindi, Malyalam, Tamil, Arabic
Jammu
3546 followers

Medical Component OfHCM

Remained Incharge Medical Officer with Hon'Ble C.M of J and K for More Than 20 Years from Jan 2000 To October 2020

Govt. Medical College, Jammu

M.S (General Surgery )

User Languages
Speaks English
Hyderabad
556 followers

20 Years of Teaching To Both UGs & PGs

As Assistant, Associate & Professor

Gandhi Medical College, Dr. NTRUHS

MD Pathology

User Languages
Speaks English, Hindi, Kannada, Telugu
Meerut
2757 followers

Anand Hospital

Neuro Intensive Care

Zhengzhou University

MBBS

User Languages
Speaks English, Hindi, Chinese (Mandarin), Russian
Pune
4976 followers

PHC Bichpuri and ESI Dispensary Chippitola Agra & SN Medical College Agra & Fatehgarh

Medical Officer Incharge

SN Medical College, Agra

DA

User Languages
Speaks English, Hindi, Marathi

Trending Cases