Hashimoto thyroiditis

An autoimmune disorder caused by the production of autoantibodies against thyroid tissue. There is progressive destruction of the thyroid follicles leading to hypothyroidism.

Disease Alternative Name

lymphocytic thyroiditis
hashimoto disease
autoimmune thyroiditis
chronic lymphocytic thyroiditis
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Concluded Case

Hashimoto thyroiditis is associated with 1) CTLA4 2) PTPN22 3) Both of the above 4) None of the above

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Concluded answer

Hashimoto thyroiditis is associated with polymorphisms in immune regulation-associated genes, including cytotoxic T lymphocyte-associated antigen-4 (CTLA4) and protein tyrosine phosphatase-22 (PTPN22), both of which code for regulators of T...


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