Johnson syndrome

A systemic, serious, and life-threatening disorder characterized by lesions in the skin and mucous membranes that may lead to necrosis. The lesions may appear anywhere in the body but they occur more commonly in the palms, soles, dorsum of the hands, and extensor surfaces. The lesions are vesicular or necrotic in the center, surrounded by an erythematous zone and occupy less than 10% of the body surfaces. The appearance of the mucocutaneous lesions is preceded by an upper respiratory tract infection. It is an immune complex hypersensitivity reaction usually caused by drugs (e.g., sulfa, phenytoin, penicillin), viruses (e.g., herpes simplex, influenza, hepatitis), and malignancies (e.g., carcinoma and lymphoma).

Disease Alternative Name

stevens-johnson syndrome

stevens johnson syndrome

erythema multiforme major

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Recent Cases of Johnson syndrome

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Dr. Akshay Maskar

General Practice

18 yr male pt C/O fever with chills on &off since 22 days No headache Mild Malaise Reddish rash at rt lower leg like petechial hemorrhages H/O loose motion and cough with exp before 1 5days back Pt had H/...See More

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Dr. Heena Ara

Dermatology (Ayurveda)

40 y/o f suffering from fever for last 3 days .3 days before some pappules erupted all over body after that it slowly tr...See More

36 Views

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, 24 Answers

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Top Cases of Johnson syndrome

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Concluded Case

Golam Mortuza

MBBS Student

46F She is on MDT for MB(Adult) Leprosy (Other) with grade I disability (ulcer on right sole) and taking Prednisolone fo...See More

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Dr. Shivraj Agarwal

General Practice

Yes this is herpes zoster You rightly put her on acyclovir Kindly give the full doses of 800mg 5times a day and tapper off gradually and keep on maintenance dose don't withdraw immidiately Second thing don't stop steroids as she on Rest loc...