Lateral sclerosis

A 52-year-old man with a 2-year history of progressive symptoms including gait disturbance, hyperreflexia, muscle weakness, skeletal muscle atrophy, spasticity, and upper motor neuron dysfunction consistent with amyotrophic lateral sclerosi...See More

Chief Complaint A 62 y/o female complains of muscle weakness in the right leg and the left leg. In a 7 months later, the muscle weakness progressed to both the arm. History Suspected diagnosis of amyotrophic lateral sclerosis was m...See More

The role of mitochondria in aging, neurodegenerative disease, and future therapeutic options :- ------------------------...See More

Pseudobulbar affect (PBA) is a condition that's characterized by episodes of sudden uncontrollable and inappropriate laughing or crying. Pseudobulbar affect typically occurs in people with certain neurological conditions or injuries, which ...See More

1. Causes of Apple core sign femur synovial chondromatosis (Most common) pigmented villonodular synovitis amyloidosis rheumatoid arthritis 2. Anterior tibial translation/translocation > 7mm is highly suggestive of Anterior cruciate ligame...See More

NEURODEGENERATIVE DISEASE WITH ASSOCIATED PROTEINS 1) A-beta Alzheimer disease 2) Tau Alzheimer disease Frontotemporal lobar degeneration Parkinson disease Progressive supranuclear palsy Corticobasilar degeneration 3) TPD-43 Frontotemp...See More

#CCAUpdates Statins could protect against motor neurone disease ▫️High cholesterol has been found to be a possible risk factor for the development of motor neurone disease (MND), according to a large study of genetic data led in the UK b...See More