Maffucci syndrome

A rare non-inherited disorder primarily affecting the skin and skeletal system. It is classified as a mesodermal dysplasia. Clinical signs appear within the first decade and are characterized by multiple soft tissue hemiangiomas and enchondromas leading to skeletal deformities. Clinical course is progressive with variable development of associated malignancies.

Disease Alternative Name

dyschondroplasia and cavernous hemangioma
enchondromatosis with hemangiomata
hemangiomata with dyschondroplasia
chondrodysplasia with hemangioma
chondroplasia angiomatosis
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