Merkel cell carcinoma

A rare malignant cutaneous tumor seen in elderly patients. Its usual location is on the head, neck and extremities. The tumor is composed of small round cells with scanty cytoplasm arranged in a trabecular pattern, or in ill-defined nodules or in a diffuse pattern. The tumor cells contain cytoplasmic membrane-bound dense core granules resembling neurosecretory granules. There is strong evidence implicating Merkel cell polyomavirus in a majority of cases of Merkel cell carcinoma.

Disease Alternative Name

trabecular skin carcinoma
merkel cell tumor
mcc
neuroendocrine carcinoma of the skin
neuroendocrine carcinoma of skin
merkel cell cancer
neuroendocrine skin carcinoma
trabecular cancer
cutaneous neuroendocrine carcinoma
cutaneous apudoma
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Tata Central Hospital, Jamadoba

Consultant Pathologist

SCBMC, Cuttack, Orissa

MD(Pathology)

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