Mesenchymal tumor

An extremely rare, benign or malignant mesenchymal tumor arising from the soft tissues. It is a distinctive tumor, which usually displays the following morphologic characteristics: low cellularity, myxoid changes, presence of spindled cells and osteoclasts, hemangiopericytoma-like vessels, hemorrhage, and osteoid-like matrix. It is associated with the presence of a paraneoplastic syndrome called osteogenic osteomalacia. This syndrome usually precedes the appearance of the tumor, and it is characterized by phosphaturia, hypophosphatemia, normal serum calcium levels, and decreased levels of 1,25-dihydroxyvitamin D3. Patients present with bone and muscle pain, severe muscle weakness, fractures, gait disturbances, skeletal deformity, height loss, and slow growth. The metabolic disturbances improve or completely disappear after the complete resection of the tumor.

Disease Alternative Name

phosphaturic mesenchymal tumor
mixed connective tissue variant
mixed connective tissue type
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Hyderabad
553 followers

20 Years of Teaching To Both UGs & PGs

As Assistant, Associate & Professor

Gandhi Medical College, Dr. NTRUHS

MD Pathology

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Pacific Medical College

Assistant Professor

M.P.SHAH MEDICAL COLLEGE

M.D.

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REWARI
18 followers

Pt. B D Sharma Postgraduate Institute of Medical Sciences

M.B.B.S

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306 followers

PGIMS Rohtak

Senior Resident

PGIMS ROHTAK

MD pathology

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Dehradun
430 followers
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Speaks English

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