14 year old male with jaundice and splenomegaly. Peripheral smar is shown below. Diagnose the case



It can be any microangiopathic hemolytic anemia since helmet cells are prominent..get a Coombs test done, malaria and give detailed history

RBC: moderate degree of anisopoikilocytosis .normocytic normochromic cells are followed by macrocytes.fair number of schistocytes and few sickle cell seen. nRBC present. R/O Hemolytic anemia and sickle cell disease

Sickle cell anemia with malaria.

TMA. Low platelets, schistocytes. In a 14 year old this is concerning for TTP or HUS. HUS- more likely presenting with history of diarrhea and renal failure.

fragmented RBCs. Microangiopathic Hemolytic anaemia

Need more history... Maybe Sickle Cell Anemia or Hereditary Spherocytosis

adv. HB electrophoresis, G6PD,DCT,LDH,osmotic fragility test for reason of hemolysis

Agree with Dr. Jain. Mahc /aiha

Hemolytic Anemia

g6pd deficiency is also a possibility - those are helmet shaped cells & some appear as ghost cells

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