56 year old male with a h/o malignancy and a lung mass. Biopsy done. Comment on HPE

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Organoid pattern of tumour, neuroendocrine tumour

Neuroendocrine tumor

Carcinoid tumor (Zell ballen pattern seen)

Undifferentiated carcinoma

Salt and pepper chromatin is lacking.

Classic zellballen pattern... Neuroendocrine tumour nice case

? metastatic deposit from renal cell carcinoma. nuclei are showing prominent nucleoli rather than salt pepper pattern

Carcinoid / Neuro Endocrine tumor with characteristic zell ballen arrangement of tumor cells...Salt and pepper nuclear chromatin

Sections examined show a well defined nest of monotonous population of tumor cells compressing the adjacent normal lung parenchyma . The individual tumor cells have small round to oval central nuclei , stippled nuclear chromatin with prominent nucleoli and abundant clear to eosinophilic granular cytoplasm .The tumor cells are separated by thin fibrovascular septae. No evidence of atypical mitosis , necrosis or haemorrhage noted .( atypical carcinoids) Impression - Biopsy Lung Mass - Well Differentiated Carcinoid Tumor ( Neuroendocrine Tumor ) Advice IHC - Synaptophysin , Chromogranin , NSE , Ki 67 Correlation with Clinical , Radiological Findings and Serum Biochemical Markers Thanku

Thers a lot to learn frm yu Dr Mohit
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Neuroendocrine tumour

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