30 years old male non diabetic male left foot ulcerative lesions

30 year old male came with this wound over the foot. suggest the treatment.

35 yr old male came with history of non-healing wounds on both legs since 5-6 years, purulent, foul smelling discharge present. No h/o trauma, no h/o long term medication, no h/o diabetes.. Patient took treatment from several doctors and RMPs before.. But not relieved. Diagnosis and management?

36 year old female patient presented with complaints of multiple episodes of blood in stools over the last few months. In addition to that she also presented with skin lesions over her legs. How to proceed in such a case? Can these two conditions can be inter-related?

52Yr/M patient having this kind of wound since 5yrs k/c/o - DM on oral medicines - 180mg/dl No HTN h/o - Eczema - used multiple home remedies. Kindly suggest Dx & Rx