Generalized oral ulcers for 1 year

A 44 y/o female presented with these generalized oral ulcers for 1 year. Her complaint started as persistent sore throat, intermittently, for several months that did not respond to antibiotics or antiviral treatment.Then she developed multiple/generalized painful oral ulcers that made it difficult for her to eat and thus lost 10 kg. At that time, she also noted abdominal and thigh ulcers and developed pain and redness in her eyes. The eye lesions responded to prednisone eye drops. How these oral lesions should be treated?

Dr. Pushker Bhomia and 18 others answered

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Stevens-Johnson syndrome Herpes labialis Cold sores Behcets symdrome Antibiotics Analgesics Ointments
* Sj syndrome Needs further investigation and evaluation to conclude and treatment plan.
Thanks Dr Sabista Naaz
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R/o S J Syndrome
Thanx dr Pushkar ji Bhomia
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According to H/0 and pic. Suggestive of "Steven's Johnson Syndrome" First Investigate after that Treat.
Erythema multiforme major. S.J.Syndrome... Stevens-Johnson syndrome is a rare, serious disorder of your skin and mucous membranes. It's usually a reaction to a medication or an infection. Often, it begins with flu-like symptoms, followed by a painful red or purplish rash that spreads and blisters. Then the top layer of the affected skin dies, sheds and then heals. Some drugs are considered to be responsible.. Allopurinol..*Carbamazepine.*Lamotrigine.* Nevirapine.The "oxicam" class of anti-inflammatory drugs (including meloxicam and piroxicam)*Phenobarbital.*Phenytoin. * Sulfamethocazole and other sulfa antibiotics.
Thanx Dr.Sebistaji
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Chronic oral ulcer for last 1 year Not responding to treatment with antibacterial or antiviral medication Adv 1)Please rule out immunosuppressive state Check for HIV and HCV 2) Look out for Autoimmune disorders which can cause chronic ulcers Send Anti nuclear antibody Anti ds DNA antibody
Recurrent apthous stomititis.clobetasol propionate gel, Oral prednisone , 5% amlexanox gel, CHX mouth wash, multivitamin, oral prophylaxis, habbit counselling if any.
Causes of recurrent oral ulcer IBD SLE Behchet disease HIV Tuberculosis Investigation-ana anca Ra esr crp For behchet...pethergy test...hla b51
SJS . Need investigations. Multivitamin supplements. Fluids more.rest. Immunocompromised state. Prednisolone for eye. ?Oral steroids.
? Behcets syndrome.will require oral steroids, azathioprine and perhaps cyclosporin.
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