AN UPDATE: COVID-19 An unusual finding........ A 33‐year‐old female health care professional, with no previous medical condition, presented with fever (39.4°C), myalgia, abdominal pain, and severe watery diarrhea 12 hours after exposure to a highly suspected case of COVID‐19. She was tachycardic, tachypneic with hypertension, and her laboratory tests showed leukocytosis with absolute lymphopenia (white blood cells = 13.6 × 103, lymphocytes = 1 × 103 [7%], serum ferritin [315 ng/mL], and d‐dimer was high normal [0.4 μg fibrinogen equivalent units/mL]). Computed tomography (CT) of the chest was normal. One day later, she developed sore throat, anosmia and ageusia, headache, generalized bone pain, and dry cough. Skin lesions started to appear in the form of sudden onset of morbilliform skin rash, erythematous patches, and urticarial lesions fading on pressure with itching mainly on the trunk; the skin lesions were extending to the upper and lower limbs including the palms; there were oral lesions in the form of oral congestion and petechiae; and sore throat and pain were referred to the ear. She was home isolated and started symptomatic treatment. Three days later, she started to take azithromycin 500 mg/d for 5 days and oseltamivir 75 mg/12 h for 5 days, but unfortunately her condition worsened and CT chest showed ground‐glass opacities and she started hydroxychloroquine per oral (PO) (400 mg /12 h for 1 day and then 200 mg/12 h for 9 days); the skin lesions started to fade out while itching continued for several days. A unique finding was seen in the form of sudden eruption of 12 wart‐like lesions on the lower extremities, of different clinical types (planter and plane) and sizes (0.2‐2 cm in diameter) which, to our knowledge, was not described before. Her general condition worsened over the next few days, she got hospitalized, rapid test for COVID‐19 was positive for immunoglobulin M (IgM), and she was prescribed intravenous methylprednisolone (1.5 mg/kg/d for 5 days), anticoagulation therapy (enoxaparine [1 mg/kg twice daily for 5 days]), and levofloxacin (500 mg/d for 5 days). After few days, she got better, nasopharyngeal swabs for COVID‐19 were negative, and discharged from hospital on pulse prednisone 80 mg PO 2 days a week for 2 weeks with gradual tapering and rivaroxaban (10 mg/d for 4 weeks) after which her condition resolved with deterioration of her warts in a slowly progressive fashion. We believe that these skin lesions were part of the COVID‐19 syndrome, as she had most of the clinical, laboratory, and imaging features associated with the disease, with positive rapid IgM test. Take away: This is the first case to report wart‐like lesions in association with COVID‐19. This may be due to the presence of subclinical infection with human papilloma virus that was dormant in skin, as a sequelae to her profession, and exacerbated by lowered immunity due to SARS‐CoV‐2 viral infection, or suggestively, the SARS‐CoV‐2 may make the host more susceptible for other viral infections. Content source: Wiley.com

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Excellentlly corelated..And authentically.. Yes,. many immunology compromised patho physiological behavioral disorders are co linked with each other. HPV is known and proved for that. Covid 1 9 is also concluded as of immunity compromised diseases. Either CAVID 19 make the situation more favourable for HPV or HPV makes COVID 19 i section more sufferable,but result is the same. Congratulations gor the post Dr.Hritmaji.

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Congratulations! Your case has been selected as Case of the day and you have been awarded 5 points for sharing the case. Keep posting your interesting cases, Happy Curofying!

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Yes i totally agree with explaination give Hpv a/w low immunity aggravated saras co v2 war5s responding to treatment a

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Very nice presentation of the case.Covid 19 with HPV infection, one may be due to the other or vice versa .Thanks Dr Nigam for the nice case history

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Impressive keep for DD

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I agree with Dr Haritma Nigam and thanks for your nice presentation of the case

Agree mam

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HPV.....covid 19 I agree??

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Callocity

Hpv and covid 19 corelation well defied

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