Cavitation in right lobe of lung.. Lobectomy specimen.. 60yr male..

3 Likes

LikeAnswersShare

Mam slides show presence of broad aseptate fungal hyphae with irregular and occasional branching at 90 degrees Impression Mucormycosis Advice special stains for fungal demonstration GMS , PAS Thanku

Respected madam, thanks for the enigmatic post. MICROSCOPY: Stained section shows eosinophilic proteinaceous material admixed with many broad, non-septate [Cenocytic], thin walled, pleomorphic hyphae with irregular, non-parallel contours with right angle branching [90 degrees]. Since the hyphae have little structural stability, they are often folded, twisted, wrinkled, or collapsed. There is dispersed brown pigment.No evidence of malignancy in the images studied. IMPRESSION : LOBECTOMY, RIGHT LUNG : SUGGESTIVE OF ZYGOMYCETES, MUCORMYCOSIS. SPECIAL STUDIES : Special stains with PAS or GMS can be used to highlight the organisms and allow a clear assessment of themorphology. DIFFERENTIAL DIAGNOSIS : Aspergillus : Thinner, septate, with regular branching and they branch at acute angles [45 degrees as opposed to 90 degrees]. Thank you very much madam, Best regards.

Respected madam.... Section shows broad Septate hyphae(ribbon shaped) with 90 degree branching at some Places.... Most probably it's mucormycosis.... But I can see scattered brownish pigment also..... And if it's not formalin pigment then such morphology with pigment leads to Chromoblastomycosis.... Advice: special stains.... Gms, pas

I would go with mucormycosis.

*Fungal ball,composed of Mucormycosis.Advised GMS stain & Testing for HIV.

the sections from lung show broad aseptate brabching ribbon like hyphae of fungus without budding along with prominent rust-brown pigmentation. IMPRESSION.. fungal infection-mucormycosis ADVICE Special stains for fungus, PAS N GMS

fungal granulomatous lesion... Mucormycosis most likely to be confirmed with PAS stain

Section shows broad hyphae n branching with mild granulation tissue formation,n inflammation, findings r in favour of fungal etiology probably mucormycosis. Adv- special stain GMS n PAS

Pulmonary koch's.

fungal infection- lung

Load more answers

Diseases Related to Discussion

Inflammation
Mucormycosis
Chromoblastomycosis