Eosinophil Count For Early Detection Of COVID-19

Eosinophil Count For Early Detection Of COVID-19 According to new research in The Journal of the American Osteopathic Association, a rapid laboratory test, the eosinophil count, readily obtained from a routine complete blood cell count (CBC) can aid in the early recognition of COVID-19 in patients, as well as provide prognostic information. Current testing, which relies on diagnosis of COVID-19 by nasopharyngeal swab PCR assay, remains unreliable due to variable turnaround time and a high false-negative rate. It was found that the absence of eosinophils on presentation can aid in early diagnosis, and in general, a persistent low count correlated with a poor prognosis for the patient. Review of the eosinophil count can be a useful tool in deciding whether to promptly isolate someone and initiate specific therapies while waiting for confirmatory test results. What does the study say? In the study, eosinopenia correlated with diagnosis of COVID-19, and its persistence correlated with high disease severity and low rates of recovery. Low eosinophil count, or eosinopenia, is defined as having < 100 cells/microliter. A healthy range is typically between 100-400 cells/microliter. Researchers compared the eosinophil results of routine CBC from the first 50 admitted COVID-19-positive patients with the eosinophil results of 50 patients with confirmed influenza infection at the time of presentation to the emergency department. STUDY: A total of 23 of the 50 patients in the COVID-19 group (46%) passed away. Eighteen out of 21 (86%) deceased patients in the COVID-19 group who initially presented with eosinopenia remained eosinopenic versus 13 out of 26 (50%) survivors who had eosinopenia on presentation. Existing testing is challenging The clinical diagnosis of COVID-19 is confirmed by laboratory testing with a reverse-transcription polymerase chain reaction (RT-PCR) assay, which remains a challenge due to limited test availability, variable turnaround time, and low sensitivity of RT-PCR. In many hospitals, test results may take days to return.



A very useful information regarding a low eosinophil count related to severity of COVID-19 disease. DLC is an important tool in the investigation of COVID-19 disease.. Besides Eosinopenia which has been revealed in this study - another important finding which has been proved early is the presence of lymphopenia - a low lymphocyte count is also seen in COVID-19 patients

To corelate Eosinophil count and early detection of Covid 19 is very logicsl and medically justified. Role of eosinophil in multiple etiology of different systemic diseases needs to be throughlly studied.

Good tool to suspect covid at earliest lyphopenia as well eosinopenia Well lot many informations are pouring daily but none is specific or helpful

Thanx dr Dinesh Gupta

Various magzine and different research papers published different studies but without 100 % conclusion. Good for healthy debate and informative.

Thanks Dr Dinesh Gupta

Nice information

Informative update

Good information. Easy to carry out the test

Very useful information


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