HOW EFFECTIVE FOSPHENYTOIN IN COMPARISON TO PHENYTOIN IN NEONATAL SEIZURE AND DOSE
Fosphenytoin is better than phenytoin Dosage 15mg/kg loading dose followed by 5 to 8mg/kg in 2divided doses
Agree with above 1. Rapid intravenous infusion 2. Less local and cardiac toxicity 3. Phenytoin 1mg/kg 4. Fosphenytoin 1.5 mg/kg
fosphenytoin is a parenterally administered prodrug of phenytoin . can b given intramuscular too n rapid infusion can given too . 75 mg of fosphenytoin is equivalent to 50 mg of phenytoin . local tissue reaction cardiac toxicity like arrhythmia n hypotension are less compared to phenytoin . dose is same
Fosphenytoin does not cause the same degree of hypotension or cardiac abnormalities, soft tissue injury as compared to phenytoin. Dose-1.5 mg/kg fosphenytoin= 1 mg/kg phenytoin.
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45 yrs old male pt has admitted with the complaints of giddiness followed by LOC for 20 mnt then recovered. . No h / o chest pain. . breathlessness. . or profuse sweating. . Pt conscious Pulse feeble BP. 90/60 mmhg. . Spo2 ..92 %..room air. 1.. clinical diagnosis? 2 . ECG FINDINGS? 3 . treatment? just now pt admitted. .I'll update further progress. . Plz share your views. .
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A 54-year-old lady presented with reeling of head for one day. She has history of syncope yesterday. She gives similar history in the past. She was sitting comfortably. Her pulse was not palpable. BP not recordable. Her heart rate was around 200 beats per minute on auscultation. Chest was clear. Diagnosis and management.
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12 yr old boy with progressive weakness in all four limb and dysarthia.
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