The most common cutaneous manifestation of MEN 1 syndrome is ____________. A. lipoma B. angiofibroma C. collagenoma D. neurofibroma

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Angiofibromas and collagenomas are markers for this tumor syndrome. In the evaluation of a cohort of patients with Zollinger-Ellison syndrome due to gastrinomas, for example, the dermatological criterion of more than 3 angiofibromas or 1 or more collagenomas was sensitive (75%) and specific (95%) for the diagnosis of MEN1.

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Answer is B Cutaneous tumors in MEN 1 : * Angiofibroma- 85% * Collagenoma- 70% * Lipoma- 33%

B

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B -Angiofibroma

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C collagenoma.

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B. Angiofibroma

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B

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B

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Collagenoma

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