What is the doses of adrnline in drug allergy

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Dr. Pankaj Jagirdar

Dermatology

Doses of Adrenaline in severe Anaphylactoid and Anaphylactic reactions Adults: Inject adrenaline 1:1000intramuscularly: Small adults (<50 kg) give 0.25 mL Average adults (50-100 kg) give 0.50 mL Large adults (>100 kg) give 0.75 mL Children (up to 25 kg) Use adrenaline 1:10 000 (Dilute 1 ampoule -1 mL of adrenaline 1:1000 with 9 mL water for injection or normal saline). Inject intramuscularly up to a maximum of 500 microgram (5 mL) according to the guide (approximates to 10 microgram/kg). 1 year (10 kg) give 1 mL 3 years (15 kg) give 1.5 mL 5 years (20 kg) give 2 mL 8 years (25 kg) give 2.5 mL Children >25 kg as for small adults If there has been little or no response to the initial intramuscular dose of adrenaline, administer 5 microgram/kg slowly into the intravenous line. Repeat at 5 minute intervals depending on response. If the patient remains shocked, start an adrenaline infusion (preferably via a central venous line), commencing at 0.25 microgram/kg/minute. REF: Anaphylaxis Wall Chart By Aust Prescr 2001;24:112 DOI: 10.18773/austprescr.2001.136