Ataxia telangiectasia

Rare hereditary disease characterized by extreme sensitivity to ionizing radiation or radiomimetic drugs because of a defect in DNA repair. AT heterozygosity is estimated to occur in more than 2% of the U.S. population; heterozygotes exhibit increased radiation sensitivity and are at increased risk for several types of cancer. The normal version of the gene that is defective in AT appears to activate the p53-dependent response to DNA damage.

Disease Alternative Name

louis-bar syndrome
ataxia-telangiectasia
ataxia telangiectasia syndrome
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Davangere
522 followers

Jagadguru Jayadeva Murugarajendra Medical College

Retired Professor and Head Pediatrics

Jagadguru Jayadeva Murugarajendra Medical College

md,frcpch(uk),ficpcc(London),masp(usa),phd, fams ,fimsa.

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MEDICAL OFFICER I/C.

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c gp.

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Visakhapatnam
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Dhanbad
767 followers

Ex.central Hospital Dhanbad.1985 ..1993..ex.pathologist .drs Tribedy and Roy Dianostic Lab.kolkata.ex Pathologist.inst of Child Health Kolkata.

Senior Pathologist

School of Tropical Medicine. Kolkata

d c p

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Meerut
2757 followers

Anand Hospital

Neuro Intensive Care

Zhengzhou University

MBBS

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