Autosomal recessive osteopetrosis type 3
An autosomal recessive form of osteopetrosis caused by mutation(s) in at least 8 genes related to osteoclast function. This condition is characterized by the failure of osteoclasts to resorb bone, resulting in impaired bone modeling/remodeling, and skeletal fragility despite increased bone mass; it is also associated with hematopoietic insufficiency, hypocalcemia, disturbed tooth eruption, nerve entrapment syndromes, and growth impairment. Some cases are also associated with progressive neurological deterioration.
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Psoriasis is often associated with other comorbidities such as psoriatic arthritis, obesity, inflammatory bowel disease, diabetes, and cardiovascular disease. Psoriasis causes increased medical costs, work limitations, as well as productivity loss. This economic burden, along with reduction in quality of life in patients prompts the need for effective disease management. Widespread disease often requires systemic treatment due to the extent of BSA involvement. Guidelines recommend treatment with biologic agents or nonbiologic agents or phototherapy with ultraviolet B (UVB) or with psoralen plus ultraviolet A (PUVA) therapy. Guidelines suggest that physicians should balance the individual patient characteristics with side-effects when making therapeutic decisions. Please share your thoughts on the same......
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A 30 years man with this skin rashes over his right scapular region What is the Dx and Rx Seniors plz guide
Dr. Irfan Khan1 Like22 Answers Aplasia cutis congenita occurs if the mother has taken ________________ medication
Drug News3 Likes21 Answers29 y F C/o- Constant dry spasmodic cough, nasal blockage,smell and test loss,. Appt- Less Thrst-Less Des- sour, Chilli Avrs- food Sweat- Scanty, Stool- Loose Sleep- Distrub due to cough Mind -Irritable, easily anger Dr suggest your opinion
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