Autosomal recessive spinocerebellar ataxia type 12

Psoriasis is often associated with other comorbidities such as psoriatic arthritis, obesity, inflammatory bowel disease, diabetes, and cardiovascular disease. Psoriasis causes increased medical costs, work limitations, as well as productivity loss. This economic burden, along with reduction in quality of life in patients prompts the need for effective disease management. Widespread disease often requires systemic treatment due to the extent of BSA involvement. Guidelines recommend treatment with biologic agents or nonbiologic agents or phototherapy with ultraviolet B (UVB) or with psoralen plus ultraviolet A (PUVA) therapy. Guidelines suggest that physicians should balance the individual patient characteristics with side-effects when making therapeutic decisions. Please share your thoughts on the same......

Topical agents are the cornerstone of treatment, either alone, or in combination with phototherapy or systemic treatments for psoriasis. Topical therapy is the treatment of choice in patients with psoriasis affecting < 10% body surface area (BSA) or for psoriasis affecting sensitive areas such as face, flexures, and genitals. They are used intermittently or continuously but more potent agents should be used for a shorter duration to avoid the side-effects. Please share your experiences with topical therapy for patients with psoriasis......

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Aplasia cutis congenita occurs if the mother has taken ________________ medication