Crohn disease

A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.

Disease Alternative Name

regional enteritis
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Concluded Case

Gene associated with Crohn disease include 1) NOD2 2) ATG16L1 3) IRGM 4) All of these

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Concluded answer

NOD2, ATG16L1, and IRGM are expressed in multiple cell types, and their precise roles in the pathogenesis of Crohn disease have yet to be defined.


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