Hemophagocytic syndrome
A classification of rare, non-neoplastic, proliferative disorders of the hematologic system. Primary or familial hemophagocytic lymphohistiocytosis (HLH) is inherited with an autosomal recessive pattern with five known subtypes differentiated by specific genetic mutations. Secondary manifestation of HLH is usually seen in hyperactivated immunologic states such as infection, autoimmune disease or malignancy. Histiocytes in the bone marrow, spleen or lymph nodes become activated to the point that phagocytosis proceeds unchecked. Clinical signs usually present within the first decade and include fever, jaundice, hepatosplenomegaly, lymphadenopathy and skin rash. Prompt initiation of treatment improves survival though prognosis remains poor even with intervention.
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Ex.central Hospital Dhanbad.1985 ..1993..ex.pathologist .drs Tribedy and Roy Dianostic Lab.kolkata.ex Pathologist.inst of Child Health Kolkata.
Senior Pathologist
School of Tropical Medicine. Kolkata
d c p
The Health City Hospital
Intensivist
Maharashtra University of Health Sciences Nashik
bhms
BCCL Hospital
Ex. Dy.Cmo
PMCH
MBBS
Parmarth Homeopathic Ausdhalay
M/O Incherge
Homeopathy University Jaipur
DHMS
Tata Central Hospital, Jamadoba
Consultant Pathologist
SCBMC, Cuttack, Orissa
MD(Pathology)
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A patient of 34 years complaining about having itching on the b/l palm region since 7-8 months and it has started from a small black patch . And it spreads in this condition. He has no history of DM and hypertension. N also No ho of smoking n alcohol.
Dr. Veenu Yadav4 Likes7 Answers - Login to View the image
Patient of Age 56 years came to the OPD with complaints of severe itching on the scalp since 2years and on plucking of hair he got some kind of relief.
Dr. Veenu Yadav1 Like6 Answers Pharma standards body Indian Pharmacopoeia Commission (IPC) has issued an alert over some commonly used medicines as they trigger adverse reactions. Commonly-used painkiller "Nimesulide" & antibiotic "Cefuroxime" can lead to serious skin disorders. In your practice and observation, have you noticed any such adverse reactions in patients in recent times?
Doc Insights0 Like4 Answers- Login to View the image
M37yrs. Pain neck referred to both hands. 6 months.
Dr. Syam Sundar Patro2 Likes4 Answers - Login to View the image
F.34yrs. Spot diagnosis please. No h/o Injury.
Dr. Syam Sundar Patro0 Like4 Answers