Langerhans cell histiocytosis
A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001)
Disease Alternative Name
Yes it's SWEET'S SYNDROME..also called Acute febrile neutrophils dermatitis The age, painful lesions on the both legs Here main clinical findings are shor duration of onset of eruptions with fever ..pathological finding is neutrophils i...
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They are characterized by inflammation and fibrosis of pulmonary interstitium
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Thrombocytosis itself is a marker of sepsis . Plus iron deficiency may contribute to it .acute phase reactants like esr take some time to come to normal . Blood c/s should have been done. Would like to see the X-ray film too.
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Recent Cases of Langerhans cell histiocytosis
Browse recently discussed Langerhans cell histiocytosis cases by specialistsTop Cases of Langerhans cell histiocytosis
Selected by editors, top cases are known for unique problem or best solutionTop Langerhans cell histiocytosis Doctors on Curofy
Top doctors who continously share their opinions on Langerhans cell histiocytosisEx.central Hospital Dhanbad.1985 ..1993..ex.pathologist .drs Tribedy and Roy Dianostic Lab.kolkata.ex Pathologist.inst of Child Health Kolkata.
Senior Pathologist
School of Tropical Medicine. Kolkata
d c p
Tata Central Hospital, Jamadoba
Consultant Pathologist
SCBMC, Cuttack, Orissa
MD(Pathology)
Private Diagnostic Centre
Senior Consultant
Private Delhi
MD (Path)
Prendas Jalaram and Vallabha Harya and Org Acneilson Marg
Psyhologist
Baroda Medical Collage
Md path
Saveetha Medical College and Hospital, Chennai
Professor of Transfusion Medicine and Senior Consultant In Pathology
Kasturba Medical College
M.B.B.S
Trending Cases
Pharma standards body Indian Pharmacopoeia Commission (IPC) has issued an alert over some commonly used medicines as they trigger adverse reactions. Commonly-used painkiller "Nimesulide" & antibiotic "Cefuroxime" can lead to serious skin disorders. In your practice and observation, have you noticed any such adverse reactions in patients in recent times?
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Epididymal cysts are fluid filled sacs that develop in the Epididymis. They occur for a number of reasons but are always benign and generally cause mild discomfort only. Dr. Vivek Jha is sharing a clinical case of "Epididymal cyst" managed with surgical expertise by him. Share your views on the case & learn new things.
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Dear doctor friends, Kindly suggest Rx. Female /55 years Diabetic Suffering from GANGRENE RIGHT FOOT *Chief Complaints* Swelling over right foot Bleeding from wound No pus Wound Not getting good *History* Diabetic type 2 *Vitals* PPS 180 BP 120/84 *Physical Examination* Deep bleeding wound but no pus *Investigations* The sonography report is attached *Diagnosis* Gangrene right feet, skin so thickened *Management* Regular dressing, controlled blood sugar, strictly following diet control
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Pneumothorax is air around or outside the lung. It may result from chest trauma, excess pressure on the lungs or a lung disease, such as COPD, cystic fibrosis, TB, Asthma etc. Correct interpretation of chest X-ray in this clinical setting & knowledge of when to request more complex imaging techniques are essential. In this learning series, we discuss the role of the chest X-Ray in the assessment of pneumothorax along with the value of CT scan. Learn & update your basic radiological approach for “Pneumothorax” & interpretation knowledge & patient care approach with this post.
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Secondary hypertension often affects younger patients & those with resistant or refractory hypertension. Identifying the underlying cause of secondary hypertension may lead to successful intervention with the potential to improve quality of life & reduce cardiovascular morbidity and mortality. Dr. Sanjay Jain is sharing a clinical case of “Secondary Hypertension - Pheochromocytoma management”. Share your views on the case.
Dr. Sanjay N Jain0 Like4 Answers
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