Langerhans cell histiocytosis

A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001)

Disease Alternative Name

langerhans cell granulomatosis
nos
not otherwise specified
histiocytosis x
lch
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Concluded Case

SWEET'S SYNDROME

50 years male with rheumatoid arthritis, presents with painful papules and nodules on both legs for 2 weeks, associated ...See More

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, 11 Answers

Concluded answer

Yes it's SWEET'S SYNDROME..also called Acute febrile neutrophils dermatitis The age, painful lesions on the both legs Here main clinical findings are shor duration of onset of eruptions with fever ..pathological finding is neutrophils i...


Concluded Case

CHRONIC INTERSTITIAL LUNG DISEASE 1) Fibrosing Idiopathic pulmonary fibrosis Nonspecific interstitial pneumonia Cryptogenic organizing pneumonia Pneumoconiosis Connective tissue disease associated Drug reaction Radiation pneumonitis 2) G...See More

83 Views

, 1 Answer

Concluded answer

They are characterized by inflammation and fibrosis of pulmonary interstitium


Concluded Case

1.4 year old FCH a case of bronchopneumonia (typical x-ray ) , was on IV Antibiotics, patent is symptomatically better , Discharged on orally Initial TC - 44000-->33000 --->10000 Platelet. 6lakhs to 8 lakhs HB --> 7.5 ---...See More

285 Views

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, 6 Answers

Concluded answer

Thrombocytosis itself is a marker of sepsis . Plus iron deficiency may contribute to it .acute phase reactants like esr take some time to come to normal . Blood c/s should have been done. Would like to see the X-ray film too.


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