Lymphoma mantle cell
An aggressive, usually diffuse non-Hodgkin lymphoma composed of small to medium sized B-lymphocytes (centrocytes). Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement. The gastrointestinal tract is the most commonly affected extranodal site by this type of non-Hodgkin lymphoma. The vast majority of cases express the t(11;14)(q13;q32) resulting in the rearrangement of the BCL-1 gene and the overexpression of cyclin D1 mRNA.
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St John's Medical College
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SRTR Medical College
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Indira Gandhi Govt Medical College
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Madras Medical College
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The Gujarat Cancer & Research Institute
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Shri M P Shah Medical College
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Nizam's Institute of Medical Sciences
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Osmania Medical College and Hospital
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