Mantle cell lymphoma

An aggressive, usually diffuse non-Hodgkin lymphoma composed of small to medium sized B-lymphocytes (centrocytes). Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement. The gastrointestinal tract is the most commonly affected extranodal site by this type of non-Hodgkin lymphoma. The vast majority of cases express the t(11;14)(q13;q32) resulting in the rearrangement of the BCL-1 gene and the overexpression of cyclin D1 mRNA.

Disease Alternative Name

classical mantle cell lymphoma
mcl
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Udaipur
270 followers

Pacific Medical College

Assistant Professor

M.P.SHAH MEDICAL COLLEGE

M.D.

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Pondicherry
145 followers

St John's Medical College

MD Pathology

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Delhi
221 followers

Lady Hardinge Medical College

MBBS student

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Hyderabad
284 followers

Nizam's Institute of Medical Sciences

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Osmania Medical College and Hospital

M.D. Pathology

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Bangalore
211 followers

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