Johnson syndrome
A systemic, serious, and life-threatening disorder characterized by lesions in the skin and mucous membranes that may lead to necrosis. The lesions may appear anywhere in the body but they occur more commonly in the palms, soles, dorsum of the hands, and extensor surfaces. The lesions are vesicular or necrotic in the center, surrounded by an erythematous zone and occupy less than 10% of the body surfaces. The appearance of the mucocutaneous lesions is preceded by an upper respiratory tract infection. It is an immune complex hypersensitivity reaction usually caused by drugs (e.g., sulfa, phenytoin, penicillin), viruses (e.g., herpes simplex, influenza, hepatitis), and malignancies (e.g., carcinoma and lymphoma).
Disease Alternative Name
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Severe form of Stevens jhonson syndrome.requires ICU management
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Symblepharon
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These are due to defects in bilirubin metabolism
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tzank smear test , it's simple to know about it by this slide
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More severe cases of Erythema Multiforme Major (EMM) may be confused with Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) in its early presentation. However skin lesions of EMM will be predominately Acral. In contrast, th...
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Yes this is herpes zoster You rightly put her on acyclovir Kindly give the full doses of 800mg 5times a day and tapper off gradually and keep on maintenance dose don't withdraw immidiately Second thing don't stop steroids as she on Rest loc...
Recent Cases of Johnson syndrome
Browse recently discussed Johnson syndrome cases by specialistsTop Cases of Johnson syndrome
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Top Johnson syndrome Doctors on Curofy
Top doctors who continously share their opinions on Johnson syndromeNational Institute of Medical Science
Md Paediatrics
National Institute of Medical Science
MD pediatrics




Gandhi Medical College
MBBS

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Lean NAFLD is commonly associated with obesity and metabolic abnormalities like DM, HT, and dyslipidemia. It is a part of a spectrum of conditions that includes fatty infiltration of the liver, nonalcoholic steatohepatitis, cirrhosis, hepatocellular carcinoma, and end-stage liver failure. Read about this condition which is underdiagnosed due to the absence of traditional risk factors......
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Drs A, B &C had an interesting conversation regarding the treatment of hyperemesis gravidarum.
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Patient aged 17yrs old boy C/o deep fissures+itching+blackish discoloration+dryness over bilateral palm and sole region along with pain and serious discharge since 10years *Chief Complaints* Patient aged 17yrs old boy C/o deep fissures+itching+blackish discoloration+dryness over bilateral palm and sole region along with pain and serious discharge since 10years O/E Auspitz sign-positive *History* Nothing significant *Vitals* BP=110/70 mmHg RR=22/min
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Congratulations to all top performers of Quick Brains Quiz. Thanks all for participation. Next Quiz is on 29th January 2023.
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