Glioblastoma

The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma, IDH-mutant), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma, IDH- wildtype). (Adapted from WHO)

Disease Alternative Name

spongioblastoma multiforme
gbm (glioblastoma)
cns
glioblastoma (gbm)
who grade iv glioma
grade iv astrocytic tumor
grade iv astrocytoma
grade iv astrocytic neoplasm
gbm
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Kerala Institute of Medical Sciences

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Zhengzhou University

MBBS

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Medical Component OfHCM

Remained Incharge Medical Officer with Hon'Ble C.M of J and K for More Than 20 Years from Jan 2000 To October 2020

Govt. Medical College, Jammu

M.S (General Surgery )

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PHC Bichpuri and ESI Dispensary Chippitola Agra & SN Medical College Agra & Fatehgarh

Medical Officer Incharge

SN Medical College, Agra

DA

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